Dasatinib 20mg Uses

Dasatinib 20mg is prescribed to:

  • Treat newly diagnosed adults with chronic myeloid leukemia (CML) in the chronic phase.
  • Manage chronic, accelerated, or blast phase CML that is resistant to or intolerant of previous treatments, including imatinib.
  • Treat Philadelphia chromosome-positive (Ph+) acute lymphoblastic leukemia (ALL) in adults.

How Does Dasatinib 20mg Work

Dasatinib inhibits specific tyrosine kinases that are overactive in cancer cells, such as the BCR-ABL protein in CML and Ph+ ALL. By blocking these enzymes, it disrupts cancer cell growth and division, reducing the number of abnormal cells in the body.

How to Use Dasatinib 20mg

  • Take Dasatinib 20mg exactly as prescribed by your healthcare provider.
  • Swallow the tablet whole with a full glass of water; do not crush, chew, or break the tablet.
  • It can be taken with or without food, but take it at the same time each day for consistent drug levels.
  • Avoid grapefruit or grapefruit juice while on this medication, as it may interfere with drug metabolism.

Important Notes

  • Follow your doctor’s recommendations regarding blood tests to monitor the effectiveness and side effects of the treatment.
  • Do not stop or alter the dosage without consulting your healthcare provider.

Side Effects

Common side effects may include:

  • Fatigue or weakness
  • Nausea or diarrhea
  • Skin rash
  • Muscle or joint pain

Rare but serious side effects include:

  • Low blood cell counts (anemia, neutropenia, or thrombocytopenia), increasing infection or bleeding risk
  • Fluid retention, which may cause swelling, shortness of breath, or chest pain
  • Severe gastrointestinal symptoms or bleeding
  • Liver or kidney function abnormalities

Drug Interactions

Dasatinib 20mg may interact with:

  • Proton pump inhibitors (PPIs) or antacids, which may reduce its effectiveness.
  • Blood thinners or anticoagulants, which may increase the risk of bleeding.
  • Medications that affect liver enzymes, such as certain antifungals or antibiotics, which may alter drug levels.

Inform your healthcare provider of all medications, supplements, and herbal products you are taking to avoid potential interactions.

Food Interactions

  • Avoid grapefruit and grapefruit juice, as they can increase Dasatinib levels and the risk of side effects.
  • Maintain a balanced diet to support overall health during cancer treatment.

Dasatinib 20mg Contraindications

This medication is not suitable for:

  • Individuals allergic to Dasatinib or any of its components.
  • Patients with severe liver impairment without medical supervision.
  • Use in pregnant or breastfeeding women, as it may harm the fetus or infant.

Precautions and Warnings

  • Inform your doctor if you have a history of liver or kidney disease, heart conditions, or bleeding disorders.
  • Use with caution if you have low blood cell counts or a weakened immune system.
  • Regular monitoring of blood cell counts and organ function is necessary during treatment.
  • Women of childbearing age should use effective contraception to avoid pregnancy during treatment.

Storage

  • Store Dasatinib 20mg tablets at room temperature, away from moisture, heat, and direct sunlight.
  • Keep the tablets in their original packaging and out of reach of children and pets.
  • Dispose of unused or expired tablets responsibly, following local disposal guidelines.

Safety Information

  • Take this medication only as directed by your healthcare provider.
  • Do not exceed the prescribed dose or discontinue use without medical advice.
  • Report any unusual symptoms, such as severe fatigue, swelling, or unexplained bleeding, to your doctor immediately.
Quantity 120, 180, 240, 60
Manufacturer Natco
Indian Brand Dasanat 20mg
US Brand Name Dasatinib, Sprycel
Generic Name Dasatinib
Dosage 20mg
Drug Type Tablets
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