Clofazimine 100mg Uses

Clofazimine 100mg is prescribed to:

  • Treat and manage leprosy, specifically for multibacillary (MB) leprosy, often in combination with other antileprosy drugs.
  • Reduce the incidence of leprosy reactions, which are inflammatory complications that can cause nerve damage and disability.
  • Treat other non-leprosy-related conditions as an off-label use, particularly those involving inflammatory dermatological conditions.

How Clofazimine 100mg Works

Clofazimine works by interfering with the growth and reproduction of mycobacteria, the bacteria responsible for leprosy, through binding to bacterial DNA and disrupting their function. It also has a potent anti-inflammatory action that helps reduce the immune response, particularly in diseases where inflammation plays a key role.

How to Use Clofazimine 100mg

To effectively use Clofazimine 100mg:

  • Take this medication orally, usually once daily or as directed by your healthcare provider.
  • Clofazimine should be taken with meals to enhance absorption.
  • It is important to continue taking this medication for the full duration prescribed, even if symptoms disappear, to prevent drug resistance and recurrence of the disease.

Side Effects

Common side effects of Clofazimine include:

  • Discoloration of the skin, eyes, and bodily fluids (turning pink to brownish-black)
  • Gastrointestinal disturbances such as nausea, abdominal pain, and diarrhea
  • Dry, itchy skin
  • Increased sensitivity to sunlight

More serious side effects that require medical attention include:

  • Persistent abdominal pain
  • Eye irritation or changes in vision
  • Psychological effects, including depression

Drug Interactions

Clofazimine can interact with other medications, including:

  • Other drugs used to treat leprosy, which may compound certain side effects
  • Stomach acid reducers (e.g., proton pump inhibitors or antacids) that might affect the absorption of clofazimine

Ensure that your healthcare provider is aware of all medications and supplements you are taking to manage potential interactions effectively.

Precautions and Warnings

  • Skin Discoloration: Patients should be counseled about the potential for skin and bodily fluid discoloration, which is harmless but can be permanent.
  • Sun Exposure: Due to increased photosensitivity, patients should use sun protection and avoid prolonged exposure to sunlight.
  • Monitoring: Regular monitoring of eye and liver function tests is recommended during long-term treatment.

Storage

Store Clofazimine at room temperature, away from direct light and moisture. Keep the container tightly closed and out of reach of children and pets.

Clofazimine 100mg is a crucial medication in the treatment of leprosy and other inflammatory conditions, providing relief from symptoms and preventing further complications. It is essential to adhere closely to the prescribed treatment regimen and to consult with healthcare professionals regularly to manage the condition effectively and safely.

Quantity 100, 200, 300, 400
Manufacturer Abbott
Indian Brand Hansepran 100mg
US Brand Name Clofazimine
Generic Name Clofazimine
Dosage 100mg
Drug Type Capsules
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