Cilostazol 50mg Uses

Cilostazol 50mg is prescribed to:

  • Improve symptoms of intermittent claudication, such as pain and cramping in the legs during walking or exercise.
  • Increase walking distances in individuals with peripheral arterial disease.

How Cilostazol 50mg Works

Cilostazol works by inhibiting the enzyme phosphodiesterase type III found in the walls of blood vessels and in blood platelets. This inhibition leads to an increase in cyclic AMP, which results in vasodilation (widening of blood vessels) and reduced platelet aggregation (clotting). These actions improve blood flow and oxygen delivery to the muscles of the legs, thereby reducing symptoms of claudication.

How to Use Cilostazol 50mg

Cilostazol 50mg should be taken as follows:

  • Administered orally, typically twice daily, at least 30 minutes before or two hours after breakfast and dinner.
  • Consistent use at the same times each day helps maintain stable drug levels in the bloodstream.
  • Follow the dosage and regimen prescribed by your healthcare provider, and do not discontinue use without consulting your doctor.

Side Effects

While taking Cilostazol 50mg, you may experience:

  • Headache
  • Diarrhea
  • Palpitations
  • Dizziness

Serious side effects that require medical attention include:

  • Severe headache
  • Irregular heartbeat
  • Swelling of the legs or ankles
  • Signs of bleeding or bruising more easily than normal

Drug Interactions

Cilostazol can interact adversely with:

  • Other medications that affect blood clotting, such as aspirin or warfarin.
  • Certain antifungal drugs like ketoconazole.
  • Specific antibiotics such as erythromycin.
  • Some types of antidepressants.

It is crucial to inform your doctor of all medications you are taking, including over-the-counter drugs and herbal supplements.

Food Interactions

Avoid consuming grapefruit or grapefruit juice while taking Cilostazol, as it can increase the medication’s blood levels, potentially leading to adverse effects.

Contraindications

Cilostazol is contraindicated in patients with:

  • History of heart failure.
  • Known hypersensitivity to any component of the medication.
  • Active bleeding disorders.

Precautions and Warnings

  • Heart Health: Patients with a history of cardiac conditions should use Cilostazol with caution.
  • Bleeding Risks: Due to its effect on platelet aggregation, monitor for signs of increased bleeding.
  • Regular Check-ups: Frequent monitoring of symptoms and side effects is recommended to adjust the treatment as necessary.

Storage

Store Cilostazol 50mg at room temperature, away from moisture and heat, in its original container. Ensure the container is tightly closed and out of reach of children and pets.

Cilostazol 50mg is an effective medication for improving mobility and quality of life in individuals experiencing symptoms of PAD and intermittent claudication. Adherence to prescribed guidelines and close monitoring by healthcare providers are essential for safe and effective treatment.

Quantity 100, 200, 300, 400
Manufacturer Cipla Limited
Indian Brand Pletoz 50mg
US Brand Name Cilostazol, Pletal
Generic Name Cilostazol
Dosage 50mg
Drug Type Tablets
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