Cilostazol 100mg Uses

Cilostazol 100mg is specifically used to:

  • Improve walking distance and reduce the pain experienced by individuals suffering from intermittent claudication.
  • Enhance overall circulation in patients with peripheral arterial disease (PAD).

This medication is not recommended for patients with heart failure or those in the acute phase of PAD, but it is beneficial for those looking to increase their physical activity without significant discomfort.

How Cilostazol 100mg Works

Cilostazol functions by inhibiting phosphodiesterase type III, an enzyme found in blood vessels and platelets. This inhibition leads to an increase in cyclic AMP within the cells, resulting in vasodilation (widening of the arteries) and inhibition of platelet aggregation (blood clots). These effects together help to improve blood flow in the arteries of the legs, facilitating easier and less painful walking.

How to Use Cilostazol 100mg

Cilostazol 100mg should be taken according to the following guidelines:

  • Typically administered twice daily, at least half an hour before or two hours after breakfast and dinner.
  • It is important to take this medication consistently at the same times each day to maintain an even level of the drug in your blood.
  • Continue to use this medication as directed by your healthcare provider, even if you feel well.

Side Effects

Common side effects of Cilostazol include:

  • Headache
  • Diarrhea
  • Dizziness
  • Heart palpitations

Serious side effects requiring immediate medical attention include:

  • Fast or irregular heartbeat
  • Swelling of the arms or legs
  • Unusual bleeding or bruining
  • Severe abdominal pain

Drug Interactions

Cilostazol can interact with several other medications, which can alter its effectiveness or increase side effects. Notable interactions include:

  • Other blood thinners such as aspirin or clopidogrel
  • Certain antifungal medications (like ketoconazole)
  • Antibiotics such as erythromycin
  • Antidepressants

Patients should always inform their healthcare provider about all medications they are currently taking, including over-the-counter drugs and herbal supplements.

Food Interactions

Grapefruit and grapefruit juice may interact with cilostazol and lead to potentially dangerous effects. Discuss the use of grapefruit products with your doctor.

Contraindications

Cilostazol is contraindicated in patients with:

  • Heart failure of any severity.
  • A history of hypersensitivity to cilostazol or any of its components.
  • Hemostatic disorders or active bleeding.

Precautions and Warnings

  • Cardiac Condition: Patients with a history of heart diseases should use cilostazol cautiously as it can cause palpitations and increased heart rate.
  • Bleeding Risk: As cilostazol inhibits platelet aggregation, there is an increased risk of bleeding. Patients should report any unusual bleeding to their doctor.
  • Regular Monitoring: Regular follow-ups to monitor symptoms and possible side effects are recommended.

Storage

Store Cilostazol 100mg at room temperature, away from direct light and moisture. Keep the medication in its original container, tightly closed, and out of reach of children and pets.

Cilostazol 100mg is effective in improving the symptoms of intermittent claudication and enhancing the quality of life for those with peripheral arterial disease when used under medical supervision. Adherence to dosing schedules and awareness of potential side effects can help achieve optimal outcomes with this medication.

Quantity 100, 200, 300, 400
Manufacturer Cipla Limited
Indian Brand Pletoz 100mg
US Brand Name Cilostazol, Pletal
Generic Name Cilostazol
Dosage 100mg
Drug Type Tablets
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