Temozolomide 100mg Uses

Temozolomide 100mg is prescribed to:

  • Treat glioblastoma multiforme in newly diagnosed patients, often in combination with radiation therapy.
  • Manage anaplastic astrocytoma or other recurrent high-grade gliomas in adults.
  • Inhibit the growth and spread of cancerous cells in the brain.

How Does Temozolomide 100mg Work

Temozolomide belongs to a class of drugs known as alkylating agents. It damages the DNA of cancer cells, disrupting their ability to replicate and grow. This targeted action helps slow or stop tumor progression, improving treatment outcomes.

How to Use Temozolomide 100mg

  • Take Temozolomide 100mg exactly as prescribed by your healthcare provider, typically once daily.
  • Swallow the capsule whole with a glass of water on an empty stomach, preferably at the same time each day.
  • Do not open, crush, or chew the capsule.
  • Your doctor may recommend periodic blood tests to monitor your response to treatment and adjust the dosage as needed.

Side Effects

Common side effects may include:

  • Nausea, vomiting, or loss of appetite
  • Fatigue or weakness
  • Constipation or diarrhea
  • Hair thinning or loss

Rare but serious side effects include:

  • Signs of infection, such as fever, chills, or persistent sore throat
  • Unusual bruising or bleeding
  • Severe allergic reactions, such as rash, swelling, or difficulty breathing
  • Liver or kidney dysfunction, with symptoms like dark urine, yellowing of the skin or eyes, or reduced urination

Drug Interactions

Temozolomide 100mg may interact with:

  • Immunosuppressive medications, which may increase the risk of infections.
  • Blood thinners, such as warfarin, which may require dosage adjustments.
  • Certain antifungal or antibiotic medications, which may affect the effectiveness of Temozolomide.

Food Interactions

  • Take the medication on an empty stomach to enhance absorption.
  • Avoid alcohol, as it may increase the risk of liver dysfunction and intensify side effects like nausea.

Temozolomide 100mg Contraindications

This medication is not suitable for:

  • Individuals allergic to Temozolomide or any of its components.
  • Patients with severe bone marrow suppression or uncontrolled infections.
  • Pregnant or breastfeeding women, as Temozolomide may harm the fetus or infant.

Precautions and Warnings

  • Inform your doctor if you have a history of liver or kidney problems, blood disorders, or weakened immunity.
  • Use effective contraception during treatment and for a period after the last dose, as Temozolomide can harm an unborn baby.
  • Regular monitoring of blood cell counts and organ function is essential during treatment.
  • Avoid contact with others who are sick, as this medication can weaken your immune system.

Storage

  • Store Temozolomide 100mg capsules at room temperature, away from moisture, heat, and direct sunlight.
  • Keep the capsules in their original packaging and out of reach of children and pets.
  • Do not handle damaged or leaking capsules; dispose of them following local regulations for chemotherapy drugs.

Safety Information

  • Use Temozolomide 100mg only as directed by your healthcare provider.
  • Do not adjust your dosage or stop taking the medication without consulting your doctor.
  • Report any unusual symptoms, such as severe fatigue, unexplained bruising, or signs of infection, to your healthcare provider immediately.
Quantity 10, 15, 20, 5
Manufacturer Cipla Limited
Indian Brand Temoside 100
US Brand Name Temodal, Temozolomide
Generic Name Temozolomide
Dosage 100mg
Drug Type Capsules
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