Sildenafil Citrate-Duloxetine 100mg-30mg

Sildenafil Citrate-Duloxetine 100mg-30mg Uses

Sildenafil Citrate-Duloxetine 100mg-30mg is prescribed to:

• Treat erectile dysfunction (ED) by improving blood flow to the penis.
• Manage premature ejaculation (PE) by delaying ejaculation and improving ejaculatory control.
• Improve overall sexual satisfaction and performance.

How Does Sildenafil Citrate-Duloxetine 100mg-30mg Work

• Sildenafil Citrate: Inhibits the enzyme PDE5, which increases cyclic guanosine monophosphate (cGMP) levels, relaxing the smooth muscles in penile blood vessels and enhancing blood flow during sexual arousal, resulting in a firm and lasting erection.
• Duloxetine: Increases serotonin and norepinephrine levels in the brain, which helps delay ejaculation by enhancing ejaculatory control and reducing sensitivity.

Together, these ingredients provide comprehensive relief for both erectile dysfunction and premature ejaculation.

How to Use Sildenafil Citrate-Duloxetine 100mg-30mg

• Dosage: Take one tablet approximately 1–3 hours before sexual activity.
• Administration: Swallow the tablet whole with water.
• Effect Duration: The effects typically last for up to 4–6 hours for Sildenafil and may provide longer-lasting ejaculatory control with Duloxetine.
• Do not take more than one tablet in a 24-hour period.

Important Notes

• Sexual stimulation is necessary for Sildenafil to work effectively.
• Avoid consuming alcohol, as it may reduce the medication’s effectiveness and increase the risk of side effects.

Side Effects

Common side effects may include:

• Headache or dizziness
• Flushing or redness of the face
• Nasal congestion or dry mouth
• Indigestion or upset stomach
• Nausea or fatigue

Rare but serious side effects include:

• Prolonged erection lasting more than 4 hours (priapism)
• Sudden vision or hearing loss
• Severe allergic reactions, such as rash, swelling, or difficulty breathing
• Chest pain or irregular heartbeat

Seek immediate medical attention if severe or persistent side effects occur.

Drug Interactions

Sildenafil Citrate-Duloxetine 100mg-30mg may interact with:

• Nitrates, such as nitroglycerin, which can cause a dangerous drop in blood pressure.
• Alpha-blockers used for high blood pressure or prostate conditions.
• Other medications for ED or PDE5 inhibitors, increasing the risk of side effects.
• Antidepressants, SSRIs, or MAO inhibitors, which may interact with Duloxetine.

Inform your doctor about all medications, supplements, and herbal products you are using to avoid potential interactions.

Food Interactions

• Avoid grapefruit or grapefruit juice, as it may increase the risk of side effects.
• Taking the medication with a heavy or high-fat meal may delay the onset of action for Sildenafil.

Sildenafil Citrate-Duloxetine 100mg-30mg Contraindications

This medication is not suitable for:

• Individuals allergic to Sildenafil, Duloxetine, or any other components of the formulation.
• Patients taking nitrates or nitric oxide donors.
• Individuals with severe heart or liver conditions.
• Men with a history of fainting or low blood pressure.
• Those with a history of seizures, bipolar disorder, or uncontrolled depression.

Precautions and Warnings

• Inform your doctor if you have a history of heart disease, high or low blood pressure, liver or kidney disorders, or mental health conditions.
• Use cautiously in men with a history of stroke, dehydration, or blood pressure instability.
• Not intended for use by women or individuals under 18 years of age.

Storage

• Store Sildenafil Citrate-Duloxetine 100mg-30mg tablets at room temperature, away from moisture, heat, and direct sunlight.
• Keep the tablets in their original packaging and out of reach of children and pets.
• Dispose of unused or expired tablets responsibly, following local disposal regulations.

Safety Information

• Use this medication only as prescribed by your healthcare provider.
• Do not exceed the recommended dosage or frequency.
• Seek immediate medical attention if you experience severe side effects, such as chest pain, fainting, or priapism.