Norfloxacin 400mg

Norfloxacin 400mg Uses

Norfloxacin 400mg is prescribed to:

• Treat urinary tract infections (UTIs), including cystitis and pyelonephritis.
• Manage gastrointestinal infections such as traveler’s diarrhea caused by susceptible bacteria.
• Address uncomplicated gonorrhea and other gynecological infections.
• Prevent infections in individuals undergoing specific urological procedures.

How Does Norfloxacin 400mg Work

Norfloxacin inhibits bacterial enzymes DNA gyrase and topoisomerase IV, essential for bacterial DNA replication and cell division. By disrupting these processes, it halts bacterial growth and eradicates the infection.

How to Use Norfloxacin 400mg

• Take Norfloxacin 400mg exactly as prescribed by your healthcare provider.
• Swallow the tablet whole with water on an empty stomach, either 1 hour before or 2 hours after a meal.
• Avoid taking it with dairy products, antacids, or supplements containing calcium, magnesium, or iron, as they can reduce absorption.
• Complete the full course of treatment, even if symptoms improve early, to prevent bacterial resistance.

Side Effects

Common side effects may include:

• Nausea or vomiting
• Diarrhea or abdominal pain
• Dizziness or headache
• Bitter or metallic taste

Rare but serious side effects include:

• Tendon inflammation or rupture, especially in older adults or those taking corticosteroids
• Severe allergic reactions, such as rash, swelling, or breathing difficulties
• Peripheral neuropathy, causing numbness, tingling, or pain in the extremities
• Clostridium difficile-associated diarrhea

Drug Interactions

Norfloxacin 400mg may interact with:

• Antacids, iron, or zinc supplements, which can reduce its absorption.
• Nonsteroidal anti-inflammatory drugs (NSAIDs), which may increase the risk of central nervous system side effects.
• Blood-thinning medications like warfarin, requiring close monitoring of clotting parameters.
• Medications that affect heart rhythm, increasing the risk of arrhythmias.

Food Interactions

• Avoid taking Norfloxacin with dairy products or calcium-fortified drinks.
• Drink plenty of water to stay hydrated and support kidney function during treatment.

Norfloxacin 400mg Contraindications

This medication is not suitable for:

• Individuals allergic to Norfloxacin or other fluoroquinolone antibiotics.
• Pregnant or breastfeeding women, unless specifically directed by a doctor.
• Children and adolescents under 18 years old, unless prescribed for specific conditions.

Precautions and Warnings

• Inform your doctor if you have a history of kidney problems, epilepsy, or heart rhythm disorders.
• Avoid prolonged exposure to sunlight or UV light, as Norfloxacin may increase photosensitivity.
• Use caution when driving or operating machinery, as this medication may cause dizziness.
• Stop use immediately and consult your doctor if you experience tendon pain or swelling.

Storage

• Store Norfloxacin 400mg tablets at room temperature, away from heat, moisture, and direct sunlight.
• Keep the tablets in their original packaging and out of reach of children and pets.
• Dispose of unused or expired tablets responsibly, following local disposal regulations.

Safety Information

• Use Norfloxacin 400mg only as directed by your healthcare provider.
• Do not skip doses or discontinue the medication early without consulting your doctor.
• Report any unusual symptoms, such as severe diarrhea, tendon pain, or allergic reactions, to your doctor immediately.