Nitrofurantoin 100mg Uses

Nitrofurantoin 100mg is prescribed to:

  • Treat urinary tract infections (UTIs) caused by specific bacteria.
  • Prevent recurrent UTIs in patients with a history of frequent infections.
  • Provide symptomatic relief from UTI-related discomfort.

How Does Nitrofurantoin 100mg Work

Nitrofurantoin works by inhibiting bacterial enzymes involved in the synthesis of proteins, nucleic acids, and cell walls, effectively halting the growth of bacteria. By targeting the bacteria that cause urinary tract infections, Nitrofurantoin helps to clear the infection and reduce inflammation in the urinary system.

Nitrofurantoin specifically concentrates in the urine, where it is most effective in treating infections of the bladder and kidneys.

How to Use Nitrofurantoin 100mg

  • Dosage: The usual dosage for the treatment of UTIs is one Nitrofurantoin 100mg capsule taken twice daily, as prescribed by your healthcare provider.
  • Administration: Swallow the capsule whole with a glass of water. Do not chew or crush the capsule.
  • Frequency: Take the medication at the same times each day for optimal effectiveness.
  • Duration: The duration of treatment is typically 5 to 7 days, depending on the severity of the infection and your doctor’s recommendation. For long-term prevention, your doctor will determine the appropriate dosing schedule.

Important Notes

  • Always complete the full course of treatment, even if symptoms improve before the prescribed end date.
  • Nitrofurantoin is most effective when taken with food to enhance absorption and reduce the risk of gastrointestinal upset.

Side Effects

Common side effects may include:

  • Nausea or vomiting
  • Diarrhea or upset stomach
  • Mild headache or dizziness
  • Darkening of urine (a harmless side effect)

Rare but serious side effects include:

  • Severe allergic reactions such as rash, swelling, or difficulty breathing
  • Lung problems, including shortness of breath, cough, or chest pain
  • Liver problems, indicated by yellowing of the skin or eyes, dark urine, or severe abdominal pain
  • Peripheral neuropathy (tingling or numbness in the hands or feet)

If you experience any severe side effects, contact your healthcare provider immediately.

Drug Interactions

Nitrofurantoin 100mg may interact with:

  • Antacids containing magnesium hydroxide, which may reduce the absorption of Nitrofurantoin.
  • Probenecid, which can increase the levels of Nitrofurantoin in the blood and lead to an increased risk of side effects.
  • Certain antibiotics or medications that affect kidney function, which may alter how Nitrofurantoin is processed in the body.

Inform your doctor about all medications, supplements, and herbal products you are using to avoid potential interactions.

Food Interactions

  • Take Nitrofurantoin 100mg with food to improve absorption and reduce the risk of gastrointestinal upset.
  • There are no significant food restrictions, but maintaining a balanced diet helps support the immune system during treatment.

Nitrofurantoin 100mg Contraindications

This medication is not suitable for:

  • Individuals allergic to Nitrofurantoin or any of the other components of the formulation.
  • Patients with severe kidney disease or impaired renal function.
  • Pregnant women, especially in the last trimester, unless prescribed by a healthcare provider.
  • Infants under one month of age due to the risk of hemolytic anemia.

Precautions and Warnings

  • Inform your doctor if you have a history of kidney disease, liver problems, or lung conditions.
  • Use cautiously in elderly patients, as they may be more prone to side effects such as lung or kidney issues.
  • This medication may cause lung problems, especially with long-term use. Notify your doctor immediately if you experience any symptoms such as shortness of breath or a persistent cough.
  • Regular monitoring of kidney and liver function may be required during prolonged use of Nitrofurantoin.

Storage

  • Store Nitrofurantoin 100mg capsules at room temperature, away from moisture, heat, and direct sunlight.
  • Keep the capsules in their original packaging and out of reach of children and pets.
  • Dispose of unused or expired medication according to local disposal regulations.

Safety Information

  • Use Nitrofurantoin 100mg only as prescribed by your healthcare provider.
  • Do not exceed the recommended dosage.
  • Seek immediate medical attention if you experience severe allergic reactions, difficulty breathing, or signs of lung problems.
Quantity 196, 294, 392, 98
Manufacturer Walter Bushnell
Indian Brand Martifur
US Brand Name Furadantin, Macrobid, Macrodantin, Nitrofurantoin
Generic Name Nitrofurantoin
Dosage 100mg
Drug Type Tablets

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