Gemifloxacin 320mg Uses

Gemifloxacin 320mg is prescribed to:

  • Treat acute bacterial exacerbations of chronic bronchitis (ABECB).
  • Manage mild to moderate community-acquired pneumonia (CAP) caused by susceptible bacteria.
  • Eliminate respiratory tract infections that are unresponsive to other antibiotics.

How Does Gemifloxacin 320mg Work

Gemifloxacin inhibits bacterial enzymes, specifically DNA gyrase and topoisomerase IV, which are essential for DNA replication and repair in bacteria. By blocking these processes, Gemifloxacin effectively stops the growth and multiplication of bacteria, helping the immune system clear the infection.

How to Use Gemifloxacin 320mg

  • Take Gemifloxacin 320mg exactly as prescribed by your healthcare provider, usually once daily for 5–7 days, depending on the infection.
  • Swallow the tablet whole with water, with or without food.
  • Avoid taking antacids, multivitamins, or supplements containing magnesium, calcium, or aluminum within 2 hours of this medication, as they may reduce its effectiveness.
  • Complete the full course of treatment, even if symptoms improve, to prevent antibiotic resistance.

Side Effects

Common side effects may include:

  • Nausea or diarrhea
  • Stomach discomfort
  • Dizziness or headache
  • Skin rash or itching

Rare but serious side effects include:

  • Tendon inflammation or rupture, particularly in older adults or those on corticosteroids.
  • Severe allergic reactions, such as swelling, difficulty breathing, or anaphylaxis.
  • Peripheral neuropathy, with symptoms such as tingling, numbness, or weakness.
  • Signs of liver damage, including yellowing of the skin or eyes, dark urine, or severe fatigue.

Drug Interactions

Gemifloxacin 320mg may interact with:

  • Antacids, sucralfate, and supplements containing magnesium, aluminum, or iron, reducing the drug’s absorption.
  • Medications that affect heart rhythm, such as antiarrhythmics or certain antidepressants, increasing the risk of QT prolongation.
  • Corticosteroids, increasing the risk of tendon rupture.
  • Warfarin, potentially increasing the risk of bleeding.

Food Interactions

  • Avoid excessive caffeine intake, as Gemifloxacin may heighten caffeine sensitivity.
  • Maintain adequate hydration during treatment to support kidney function and reduce side effects.

Gemifloxacin 320mg Contraindications

This medication is not suitable for:

  • Individuals allergic to Gemifloxacin, other fluoroquinolones, or any of its components.
  • Patients with a history of tendon disorders related to fluoroquinolones.
  • Individuals with known QT prolongation or uncorrected electrolyte imbalances.

Precautions and Warnings

  • Inform your doctor if you have a history of heart conditions, seizures, or kidney disease.
  • Avoid prolonged exposure to sunlight or artificial UV light, as Gemifloxacin may increase sun sensitivity.
  • Pregnant or breastfeeding women should consult their doctor before using this medication.
  • Use with caution in elderly patients, as they may be at higher risk for tendon issues and side effects.

Storage

  • Store Gemifloxacin 320mg tablets at room temperature, away from moisture, heat, and direct light.
  • Keep the tablets in their original packaging and out of reach of children and pets.
  • Dispose of unused or expired medication responsibly, following local regulations.

Safety Information

  • Use Gemifloxacin 320mg only as directed by your healthcare provider.
  • Do not share this medication with others, even if they have similar symptoms.
  • Report any unusual symptoms, such as severe tendon pain, irregular heartbeat, or neurological changes, to your healthcare provider immediately.
Quantity 100, 150, 200, 50
Manufacturer Lupin Ltd
Indian Brand G-Cin
US Brand Name Factive | Gemifloxacin
Generic Name Gemifloxacin
Dosage 320mg
Drug Type Tablets
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