Uses of Fluticasone Furoate (100mcg) + Vilanterol (25mcg)

Fluticasone Furoate + Vilanterol is used for:

  • Asthma Maintenance: Helps reduce inflammation and prevent asthma symptoms in adults and children (depending on approval for age).
  • COPD Management: Provides long-term control of airflow obstruction and reduces the frequency of exacerbations in individuals with COPD.

This combination ensures both inflammation control and sustained bronchodilation for improved breathing.

How Does Fluticasone Furoate (100mcg) + Vilanterol (25mcg) Work?

This combination medication works in two complementary ways:

  • Fluticasone Furoate: A corticosteroid that reduces inflammation in the airways, decreasing swelling and mucus production. This helps prevent symptoms such as wheezing and difficulty breathing.
  • Vilanterol: A long-acting beta2-adrenergic agonist (LABA) that relaxes the muscles around the airways, leading to prolonged bronchodilation. This allows easier airflow and sustained relief from breathing difficulties.

Together, these components provide comprehensive management of respiratory conditions.

How to Use Fluticasone Furoate (100mcg) + Vilanterol (25mcg)

  • Dosage: The typical dosage is one inhalation once daily, at the same time each day.
  • Administration: Use the inhaler as directed by your doctor. Rinse your mouth with water after use to prevent fungal infections like oral thrush. Do not swallow the rinse water.
  • Consistency: Take the medication daily, even when you feel well, to maintain control of asthma or COPD symptoms.
  • Missed Dose: If you forget a dose, take it as soon as you remember. If it is close to your next scheduled dose, skip the missed dose and continue with your usual dosing schedule. Avoid taking extra doses to make up for the missed one.

Follow your healthcare provider’s instructions for proper inhaler technique to ensure optimal delivery of the medication.

Side Effects

Common side effects of Fluticasone Furoate + Vilanterol include:

  • Headache
  • Throat irritation
  • Hoarseness or voice changes
  • Cough
  • Runny or stuffy nose

Serious but less common side effects include:

  • Increased risk of pneumonia in individuals with COPD
  • Fungal infections (oral thrush)
  • Adrenal insufficiency
  • Irregular heartbeat or chest pain
  • Severe allergic reactions (rash, swelling, or difficulty breathing)

Seek medical attention if you experience severe side effects or symptoms that persist.

Drug Interactions

Fluticasone Furoate + Vilanterol may interact with other medications, potentially altering their effects or increasing side effects. Common interactions include:

  • Beta-blockers: May reduce the effectiveness of Vilanterol.
  • Diuretics: May increase the risk of low potassium levels.
  • Antifungals and Antibiotics (e.g., Ketoconazole, Clarithromycin): Can increase the levels of Vilanterol, heightening the risk of side effects.
  • Monoamine Oxidase Inhibitors (MAOIs): May enhance the cardiovascular effects of Vilanterol.
  • Corticosteroids: Concurrent use may increase the risk of adrenal suppression.

Inform your doctor about all medications and supplements you are taking before starting this treatment.

Food Interactions

There are no significant food interactions with this medication. However, consider the following:

  • Grapefruit Juice: May increase blood levels of Vilanterol, potentially leading to side effects.
  • Alcohol: Should be avoided if it exacerbates respiratory symptoms.

Discuss dietary considerations with your healthcare provider.

Contraindications

Fluticasone Furoate + Vilanterol should not be used in the following cases:

  • Known allergy or hypersensitivity to any component of the medication.
  • Primary treatment for acute bronchospasm or asthma attacks.
  • Co-administration with other long-acting beta2-agonists, which may increase the risk of overdose.

Always consult your doctor to ensure this medication is appropriate for your condition.

Precautions and Warnings

  • Asthma-Related Death: LABAs like Vilanterol may increase the risk of asthma-related death when used alone. This combination should only be used for asthma in conjunction with an inhaled corticosteroid.
  • Infections: Prolonged use of corticosteroids may suppress the immune system, increasing the risk of infections like pneumonia or fungal infections.
  • Bone Health: Long-term use may reduce bone density; adequate calcium and vitamin D intake is recommended.
  • Adrenal Suppression: High doses or prolonged use may suppress adrenal gland function.
  • Pregnancy and Breastfeeding: Use only if clearly needed and under medical supervision.

Safety Information

  • Emergency Situations: Keep a short-acting bronchodilator (e.g., albuterol) on hand for acute symptoms or attacks.
  • Overdose: Symptoms of overdose may include rapid heart rate, shakiness, or high blood pressure. Seek immediate medical attention if an overdose occurs.
  • Regular Monitoring: Routine check-ups with your doctor are necessary to assess the effectiveness and side effects of treatment.
  • Storage Precautions: Keep the inhaler out of reach of children and pets to prevent accidental use.

Storage

  • Temperature: Store the inhaler at room temperature, ideally between 20–25°C (68–77°F). Avoid exposure to extreme heat or cold.
  • Moisture and Light: Keep the device in a dry place, away from direct sunlight. Avoid storing it in bathrooms.
  • Safety: Ensure the inhaler is capped when not in use to protect it from contamination.
  • Disposal: Dispose of the inhaler properly once the dose counter shows zero or after its expiration date. Do not puncture or incinerate the inhaler.
Quantity 120, 30, 60, 90
Manufacturer Cipla Limited
Indian Brand Voltido 100mcg/25mcg 15's
US Brand Name Breo Ellipta
Generic Name Fluticasone Furoate + Vilanterol
Dosage 100mcg-25mcg
Drug Type Tablets
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