Combiflam Uses

Combiflam is prescribed to:

  • Relieve pain and inflammation caused by arthritis, muscle injuries, and joint disorders.
  • Manage mild to moderate pain, such as headaches, toothaches, and menstrual cramps.
  • Reduce fever and discomfort associated with infections.
  • Provide relief from post-operative pain and other acute painful conditions.

How Does Combiflam Work

  • Ibuprofen: A non-steroidal anti-inflammatory drug (NSAID) that blocks cyclooxygenase (COX) enzymes, reducing the production of prostaglandins responsible for pain, inflammation, and swelling.
  • Paracetamol: Acts centrally on the brain’s pain-regulating center to relieve pain and reduce fever by lowering body temperature.

How to Use Combiflam

  • Take Combiflam exactly as prescribed by your healthcare provider, usually 1 tablet every 6–8 hours as needed.
  • Swallow the tablet whole with water after meals to reduce stomach irritation.
  • Avoid exceeding the maximum daily dose of 3–4 tablets unless directed by your doctor.
  • Follow your doctor’s advice regarding the duration of use, especially for chronic conditions.

Side Effects

Common side effects may include:

  • Nausea or upset stomach
  • Dizziness or drowsiness
  • Indigestion or mild heartburn

Rare but serious side effects include:

  • Stomach ulcers or gastrointestinal bleeding, with symptoms like black stools or blood in vomit
  • Allergic reactions, such as rash, swelling, or difficulty breathing
  • Liver dysfunction, indicated by yellowing of the skin or eyes
  • Kidney issues, with symptoms like reduced urination or swelling

Drug Interactions

Combiflam may interact with:

  • Other NSAIDs, increasing the risk of stomach or kidney problems.
  • Blood-thinning medications like warfarin, increasing the risk of bleeding.
  • Diuretics and antihypertensive drugs, potentially reducing their effectiveness.
  • Alcohol, which may enhance the risk of gastrointestinal and liver side effects.

Food Interactions

  • Take Combiflam with food or milk to minimize stomach irritation.
  • Avoid excessive alcohol consumption during treatment to reduce the risk of liver damage.

Combiflam Contraindications

This medication is not suitable for:

  • Individuals allergic to Ibuprofen, Paracetamol, or other NSAIDs.
  • Patients with active gastrointestinal ulcers or bleeding.
  • Individuals with severe liver or kidney impairment.
  • Pregnant women in their third trimester, unless specifically advised by a doctor.

Precautions and Warnings

  • Inform your doctor if you have a history of liver disease, kidney problems, or cardiovascular conditions.
  • Use with caution in elderly patients, as they may be more prone to side effects.
  • Pregnant or breastfeeding women should consult their doctor before using Combiflam.
  • Avoid prolonged use unless advised by your healthcare provider.

Storage

  • Store Combiflam tablets at room temperature, away from heat, moisture, and direct sunlight.
  • Keep the tablets in their original packaging and out of reach of children.
  • Dispose of unused or expired tablets responsibly, following local disposal guidelines.

Safety Information

  • Use Combiflam only as directed by your healthcare provider.
  • Do not skip doses or stop the medication abruptly without consulting your doctor.
  • Report any unusual symptoms, such as severe stomach pain, black stools, or allergic reactions, to your doctor immediately.
Quantity 120, 180, 240, 60
Manufacturer Sanofi India Ltd
Indian Brand Combiflam
US Brand Name Ibrufen-Paracetamol
Generic Name Ibrufen-Paracetamol
Dosage 400mg-325mg
Drug Type Tablets
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