Carbamazepine 400mg Uses

Carbamazepine 400mg is prescribed for:

  • Epilepsy: Controls partial seizures and generalized tonic-clonic seizures effectively.
  • Trigeminal Neuralgia: Relieves severe facial nerve pain.
  • Bipolar Disorder: Helps stabilize mood swings and prevents manic or depressive episodes.

It is particularly suitable for patients requiring a higher dose to manage severe or resistant conditions.

How Does Carbamazepine 400mg Work?

Carbamazepine 400mg works by stabilizing the electrical activity in the brain. It blocks sodium channels in nerve cells, reducing the rapid firing of signals responsible for seizures and nerve pain. For bipolar disorder, it regulates neurotransmitters, helping maintain emotional balance and prevent extreme mood swings.

How to Use Carbamazepine 400mg

  1. Dosage: Take Carbamazepine 400mg as directed by your doctor. Dosage depends on the condition being treated and your response to the medication.
  2. Administration: Swallow the tablet whole with water, preferably with meals to reduce stomach upset. Do not crush or chew the tablet.
  3. Regular Use: For optimal effectiveness, take the medication consistently at the same time each day.
  4. Do Not Stop Abruptly: Stopping suddenly can lead to withdrawal symptoms or seizure recurrence. Always consult your doctor before making changes.

Side Effects

Common side effects of Carbamazepine 400mg include:

  • Dizziness or drowsiness
  • Nausea or vomiting
  • Fatigue or weakness
  • Dry mouth
  • Unsteadiness

Severe side effects, such as skin rash, blurred vision, or mood changes, require immediate medical attention. Regular monitoring helps minimize risks.

Drug Interactions

Carbamazepine 400mg can interact with other medications, potentially altering their effectiveness or increasing the risk of side effects. Inform your doctor if you are taking:

  • Antidepressants
  • Antipsychotics
  • Blood thinners (e.g., warfarin)
  • Birth control pills (effectiveness may be reduced)
  • Other anticonvulsants (e.g., valproic acid, phenytoin)

Food Interactions

Avoid grapefruit or grapefruit juice while taking Carbamazepine 400mg, as it can increase the drug’s levels in your bloodstream, raising the risk of side effects. Limit alcohol intake, as it may amplify dizziness or drowsiness caused by the medication.

Contraindications

Carbamazepine 400mg is contraindicated in individuals who:

  • Are allergic to Carbamazepine or related medications like tricyclic antidepressants
  • Have a history of bone marrow suppression
  • Have severe liver or kidney impairment
  • Are taking monoamine oxidase inhibitors (MAOIs)

Precautions and Warnings

  • Pregnancy and Breastfeeding: Consult your doctor before using Carbamazepine if you are pregnant, planning to become pregnant, or breastfeeding. This medication may harm an unborn baby.
  • Monitoring: Regular blood tests are necessary to monitor blood counts, liver, and kidney function.
  • Driving and Machinery: Avoid activities requiring alertness, such as driving, until you know how the medication affects you.

Storage

Store Carbamazepine 400mg at room temperature, away from moisture and direct sunlight. Keep it out of reach of children and pets. Dispose of expired or unused medication responsibly.

Quantity 100, 200, 300, 400
Manufacturer Novartis
Indian Brand Tegrital 400mg
US Brand Name Carbagen, Carbagen SR, Carbamazepine, Carbatrol, Carbatrol XR, Epitol, Epitol XR, Tegretol, Tegretol XR, Teril, Teril XR
Generic Name Carbamazepine
Dosage 400mg
Drug Type Tablets
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