Bicalutamide

How Does Bicalutamide Work?

Bicalutamide binds to androgen receptors in prostate cancer cells, preventing testosterone from stimulating cancer growth. This slows the progression of the disease and can improve survival rates in patients with metastatic prostate cancer.

It is often used in combination with luteinizing hormone-releasing hormone (LHRH) agonists, such as leuprolide or goserelin, to enhance its effect.

Bicalutamide Uses

1. Advanced Prostate Cancer

• Used as first-line therapy for metastatic prostate cancer.
• Often combined with LHRH agonists for maximum effectiveness.
• Helps shrink tumors and delay cancer progression.

2. Locally Advanced Prostate Cancer

• Can be used as a standalone therapy or after radiation therapy.
• Reduces the risk of cancer recurrence.

3. Off-Label Uses (Experimental/Investigational)

• Some studies explore its use in hormone therapy for transgender women.
• Investigated for excessive hair growth (hirsutism) and acne in women with PCOS.

Bicalutamide Dosage Guide

The dosage depends on the stage of prostate cancer and whether it’s being used alone or with other treatments.

Bicalutamide 50mg Dosage

• Standard dose: 50mg once daily, usually at the same time each day.
• Combination therapy: Often paired with an LHRH agonist.
• Duration: Treatment is long-term and requires regular monitoring.

Administration Instructions

• Take once daily, with or without food.
• Swallow whole with water—do not crush or chew.
• Consistency is key—missing doses can affect treatment effectiveness.

Who Should Not Take Bicalutamide?

Bicalutamide may not be suitable for certain individuals. Avoid use if you:
 Are allergic to Bicalutamide or its ingredients.
 Are pregnant or breastfeeding (not intended for use in women).
 Have severe liver disease.
 Are taking medications that may interact negatively.

Bicalutamide Side Effects

While Bicalutamide is generally well-tolerated, it can cause side effects.

Common Side Effects:

 Hot flashes
 Breast swelling/tenderness (gynecomastia)
 Decreased libido or erectile dysfunction
 Fatigue and weakness
 Nausea or stomach discomfort

Less Common But Serious Side Effects:

 Liver toxicity (jaundice, dark urine, yellowing of the skin)
 Shortness of breath or lung inflammation
 Severe allergic reactions
 High blood sugar levels

If you experience any severe side effects, contact your doctor immediately.

Bicalutamide Drug Interactions

Avoid taking Bicalutamide with:

• Warfarin (may increase bleeding risk).
• Certain anti-seizure medications (like phenytoin).
• CYP3A4 inhibitors or inducers, which can affect drug metabolism.

Always inform your doctor about all medications and supplements you’re taking.

How Long Does Bicalutamide Take to Work?

• Effects start within weeks, but full benefits take months.
• Regular PSA tests are needed to monitor progress.

What Happens if You Miss a Dose?

• Take it as soon as you remember.
• If it’s close to the next dose, skip the missed one—do not double up.

Where to Buy Bicalutamide Online?

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Child Product

Bicalutamide 50mg – Standard treatment for prostate cancer.

Storage and Handling

• Store at room temperature (15-30°C / 59-86°F).
• Keep in a dry place, away from moisture and direct sunlight.
• Keep out of children’s reach.

Final Thoughts

Bicalutamide is a powerful anti-androgen therapy for managing prostate cancer. It helps slow cancer progression, improve survival, and enhance quality of life.

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