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Sinemet (Carbidopa-levodopa)


Generic for Sinemet for Parkinson's disease - Prescription Drug Information


Generic Name - Carbidopa-levodopa

Category - Antidyskinetic medication.

Indications

Parkinson's disease.

Generic Sinemet is indicated to treat Parkinson's disease. The combination of Levodopa and Carbidopa work together as an effective cure. Levodopa can help correct an imbalance of chemicals in the brain caused by Parkinson's disease. Levodopa will not cure Parkinson's disease, but will help to control the symptoms. Carbidopa helps levodopa work better, and this can decrease some side effects, such as nausea.

Generic for Sinemet Contraindications and Drug Interactions

Generic Sinemet is contraindicated in patients, who are hypersensitive to this drug, medications that belong to this class of drugs or had an allergic reaction to it in the past.

Generic Sinemet should not be taken by patients who have a history of the following ailment conditions.

depression or other mental illness
diabetes
glaucoma
heart disease, including history of a heart attack]
irregular heart beat
kidney disease
liver disease
melanoma or suspicious skin lesions
seizure disorder
stomach or intestinal ulcers

There are a number of medications that interact with Generic Sinemet. It is important to take the doctor's counsel if you are taking any of the following.

Cocaine
droperidol
furazolidone
isoniazid, INH
iron supplements
kava kava
linezolid
medicines for high blood pressure
medicines for depression, avoid those called MAO inhibitors
medicines for mental problems and psychotic disturbances
metoclopramide
papaverine
phenytoin
procarbazine
water pills

Generic for Sinemet Dosage

The following information just highlights the general average dosage of GenericSinemet
The usual recommended dosage of Generic Sinemet for Parkinson's disease is,

For clients not receiving levodopa,

Initial: 1 tablet of 10 mg carbidopa/100 mg levodopa t.i.d.-q.i.d. or 25 mg carbidopa/100 mg levodopa t.i.d.; then, increase by 1 tablet q 1-2 days until a total of 8 tablets/day is taken. If additional levodopa is required, substitute 1 tablet of 25 mg carbidopa/250 mg levodopa t.i.d.-q.i.d.

For clients receiving levodopa,

Initial: Carbidopa/levodopa dosage should be about 25% of prior levodopa dosage (levodopa dosage is discontinued 8 hr before carbidopa/levodopa is initiated); then, adjust dosage as required. Suggested starting dose is 1 tablet of 25 mg carbidopa/250 mg levodopa t.i.d.-q.i.d. for clients taking more than 1500 mg levodopa or 25 mg carbidopa/100 mg levodopa for clients taking less than 1500 mg levodopa.

Generic for Sinemet Adverse Effects

Some of the most serious Generic Sinemet side Effects include difficulty passing urine, dizziness, lightheadedness, or fainting spells, fast or irregular heartbeat (palpitations),mental depression and mood changes such as aggressive behavior or hallucinations.

This is not a complete list of all Side effects. Do concur with your doctor and follow his directions completely when you are taking Generic Sinemet.

Generic for Sinemet and Pregnancy

Studies do not indicate whether Generic Sinemet will harm an unborn baby if taken during pregnancy. Do consult your and seek medical opinion.

Generic for Sinemet and Breastfeeding

It is not known whether Generic Sinemet will harm a nursing infant. Do not take Sinemet without first talking to your doctor if you are breast-feeding a baby.

Generic for Sinemet and Pediatric

The safety and effectiveness of Generic Sinemet in pediatric patients have not been established.

Generic for Sinemet and Geriatric

The safety and effectiveness of Generic Sinemet in geriatric patients have not been established.

Note

The above information about Generic Sinemet serves as an information resource only and is not intended to substitute professional medical advice, examination, diagnosis and treatment. Always seek the counsel of your doctor, physician or pharmacist before starting any new treatment or making changes to existing therapy.


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