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Hypercholesterolemia
 

What should I know about Hypercholesterolemia?

Hypercholesterolemia refers to levels of cholesterol in the blood that are higher than normal. Though cholesterol is often associated with heart disease and obesity it is very important for growth or living. Cholesterol helps build many substances including the cell membrane of every cell in our body. Our body needs certain amount of cholesterol, however, the liver produces them in excess which gets deposited in tissues and arteries. This excess cholesterol causes these tissues and arteries to narrow and block the passage of blood to vital organs such as the brain and the heart. It can also weaken the artery, causing it to enlarge and produce an aneurysm. This process is termed "arteriosclerosis".

Cholesterol has been divided into two major categories: low-density Lipoprotein (LDL), the so-called "bad" cholesterol, and high-density Lipoprotein (HDL), the so-called "good" cholesterol. Diet, exercise, smoking, alcohol, and certain illnesses can affect the levels of both types of cholesterol.

What causes Hypercholesterolemia ?

Hypercholesterolemia is caused by excess lipids or fatty substances in the blood and is an important risk factor in developing atherosclerosis and heart disease. Genetic factors also play a vital role in developing hypercholesterolemia. Mental stress, physical activity and change in body weight can also influence the level of blood cholesterol. Inactivity can increase it and exercise can decrease it.

What are the likely symptoms of Hypercholesterolemia ?

A strong family history of early myocardial infarction ( heart attack).

  • Elevated and therapy-resistant levels of LDL in either or both parents.
  • Xanthomas (lesions caused by cholesterol deposits).
  • Cholesterol deposits in the eyelids (Xanthelasmas).
  • Chest pain ( angina ) associated with coronary artery disease.
  • Evidence of obesity.

How to prevent Hypercholesterolemia ?

The best way to prevent hypercholesterolemia is to strike a balance between your height and weight Changing dietary habits by reducing the amount of fat and cholesterol consumed is advised. Don't smoke if you have high levels of cholesterol. Increasing levels of fiber in the diet by including foods such as beans, raw fruits, whole grains and vegetables is recommended. It is important to exercise on a regular basis. Aerobic exercise is especially helpful in reducing serum cholesterol levels.

People from families with a strong history of early heart attacks should be evaluated with a lipid screen. Proper diet, exercise and the use of effective drugs can reduce serum lipid levels.

Nutrition and cardiac experts offer the following suggestions:

  • purchasing low-fat or fat-free dairy products such as milk, cheese, sour cream, and yogurt
  • eating lean red meats, chicken without skin, and fish
  • reducing consumption of foods high in saturated fat such as french fries
  • avoid foods that are rich sources of cholesterol such as eggs, liver, cheese, and bacon
  • eating smaller servings
  • keeping a food journal and writing down everything eaten each day
  • prepare food by microwaving, boiling, broiling, or baking food instead of frying
  • trimming the fat from meat before cooking it.

In families with a history of hypercholesterolemia, genetic counseling is of benefit, especially if both parents are affected. Prevention of early heart attacks require recognition of existing elevated LDL levels, and a low-cholesterol, low-saturated fat, high-unsaturated fat diet in high-risk people may help to control LDL levels.

What medications are used to treat Hypercholesterolemia ?

Some of the medications prescribed for hypercholesterolemia include

Altocor Crestor Lipitor
Lovastatin Mevacor Pravachol
Zocor  

 

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